Description
Glivec (Imatinib Mesylate)400mg Online
Glivec (Imatinib Mesylate) is an anti-cancer medication primarily used as a treatment for leukaemia, however, it may also be used to treat other types of rare cancer, such as GIST (gastrointestinal stromal tumours) and DFSP (dermatofibrosarcoma). This medicine works by inhibiting the action of the abnormal protein (called c-kit) that causes the multiplication and growth of the cancer cells, thereby preventing the spread of cancer.
Gleevec is a protein tyrosine kinase inhibitor that targets BCR-ABL, an abnormal tyrosine kinase produced by the Philadelphia chromosome mutation in people with certain types of leukemia. It also inhibits other receptor tyrosine kinases including platelet-derived growth factor (PDGF), stem cell factor (SCF), and c-KIT. Studies showed that Gleevec inhibits the proliferation of leukemia cells and other cells that grow out of control in blood cancers, and slows the progression of the gastrointestinal stromal tumor. It was one of the first targeted therapies, approved in 2001.
Gleevec can cause depletion of red blood cells (anemia), white blood cells (neutropenia), and platelets (thrombocytopenia), which can lead to infections and easy bleeding. Potentially serious side effects may include severe swelling or edema, heart, liver, and kidney problems, gastrointestinal damage, severe skin reactions, and tumor lysis syndrome, a reaction that can occur when cancer cells die suddenly.
Gleevec may cause fetal harm if used during pregnancy. While you are being treated with this medicine, it is important to tell your doctor about any side effects which you experience. In rare cases, severe reactions are possible. See your doctor immediately if you notice bloody stools, weight gain, urinating more than usual at night, coughing up blood, or bleeding of the eye. Remember that in addition to the side effects listed here, other reactions (which also require immediate medical care) may occur. Ask your doctor for more details.
