Description
Hepcvir (Sofosbuvir) 400mg Tablets Online
Hepcvir Tablet (Sofosbuvir) is a potent first-in-class nucleos(t)ide inhibitor that has recently been approved for the treatment of hepatitis C. The drug has high efficacy, low toxicity, a high resistance barrier, and minimal drug interactions. When used in combination with ribavirin or another direct-acting antiviral agent, it has revolutionized the HCV treatment spectrum. This infographic highlights the indication, dosing, and administration of sofosbuvir in chronic hepatitis C management.
Sofosbuvir is a direct-acting antiviral (DAA) agent against the hepatitis C virus (HCV). It is an inhibitor of the HCV NS5B RNA-dependent RNA polymerase, which is essential for viral replication. Sofosbuvir is a nucleotide prodrug that undergoes intracellular metabolism to form a pharmacologically active uridine analog triphosphate (GS-461203), which can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator.
Sofosbuvir pellets can be swallowed (without chewing) or they can be taken with food. To prepare a dose of sofosbuvir pellets with food, sprinkle the entire packet of pellets on one or more spoonfuls of cold or room temperature non-acidic soft food such as pudding, chocolate syrup, mashed potato, or ice cream. Take the entire mixture within 30 minutes of sprinkling the pellets on food. To avoid a bitter aftertaste, do not chew the pellets.
